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Objective To evaluate the response and toxicity of the chemo-radiotherapy assisted with Shenqi Fuzheng injection(SFI)in non-small-cell lung cancer(NSCLC).Methods 58 cases of NSCLC(from Jun.2004 to Dec.2006)were divided at random into two groups.30 cases(trial group)were given chemo-radiotherapy with Shenqi Fuzheng injection while another 28 cases(control group)only chemo-radiotherapy.The radiotherapy was carried out between two cycles of induction chemotherapy with NVB 25 mg/m2 d1,8,DDP 30 mg/m2 d1-3.The radiation dose was 60 Gy/30 f/6 W.Shenqi Fuzheng injection was used in 250 ml/d,for 21days as one cycle and after 7 day intervals, given another one cycle.The cycles of same regimen chemotherapy were given again after one week when the radiotherapy had been completed.Results Shortterm therapeutic effectiveness.the rates of complete remission and partial remission as well as the overall effective rates in patients of the trial group and control group were 16.7%,60.0%and 76.7%,and 10.7%,50.0%and 60.7%,respectively,the differences between two groups be not significant(P＞0.05).The 0.5,1,2year survival rates in patients of the trial group and control group were 96.7%,65.2%,45.0%and 89.3%,48.0%,35.0%,respectively,the differences between two groups were not significant(P＞0.05).Shenqi Fuzheng injection was shown to have changes in chemo-radiotherapy effects on clinical symptom,quality of life (QOL)and immune function and toxicity in the treatment of patients with NSCLC(P＜0.05).Conclusion Shenqi Fuzheng injection is shown to have changes in ehemo-radiotherapy effects on clinical symptom,QOL and immune function and toxicity in the treatment of patients with NSCLC,but it could not increase survival rate of the patients.
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Objective To evaluate the recent curative efficacy and security of High Intersity Focused Ultrasound(HIFU)in treating patients with advanced pancretic carcinoma.Methods 17patients with cancer of pancreas were treated by FEP-BY02,received 135(average 8)times.Results The overall response rate was 70%(CR+PR),including11.76%(2/17)complete response(CR)and 58.82%(10/17)partial response(PR).The clinical benefit response(CBR)was 82.36%.The inefficiency was 17.64%(3/17).The cancer pain was relieved in 80% patients(8/10).Nocomplications occurred.such as pancreatic juice leakage,bleeding,perforation of gastrointestinal tracts,scalding of skin in the group.Conclusions The preliminary results show that HIFU has a high efficacy and quite safety for advanced pancreatic carcinoma,it is worthy of futher clinical trail.
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It is difficult to resect completely for brain glioma with surgery because of the characteristic of strong invasion and no obvious verge with the brain tissue, and result in easily recurrentshort life time and high mortality. Radiotherapy is important for patients after surgery. The factor of prognosis include ageKarnofsky score, pathology and degree of invasion. Recently, the improvement of new equipment and technology provide the more approach for brain glioma. The paper make a summary of current situation and progress for radiotherapy of brain glioma.
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Purpose:To study the effects and efficacy of three-dimensional conformal radiotherapy (3-DCRT) for brain gliomas. Methods:Thirty cases of brain gliomas were treated by three-dimensional conformal radiotherapy.Of these 21 patients had nesidual tumor after operation, 5 were post-operative recurrent patients and 4 were post-radiotherapy recurrent patients.The total irradiation dose was 42 Gy(BED 56 Gy). All patients received 6 Gy/F.qod.Results:In the 1-3 months after 3-DCRT,the results examined by CT or MRI showed that in the 30 patients,these were CR 40.0%,PR (33.3%), NC 20.0%, PD 6.7%,The total response rate was (CR+PR) 73.3%.No acute or chronic radiation side effects were observed in the follow up .The 0.5-,1-,2-,3-year survival rates were 93.3%,77.8%,71.31%,53.18% respectively.Conclusions:The result shows that 3-DCRT of brain gliomas can improve therapeutic effect.